Table 4.

Esophageal pH measurements (mean ± SD) off proton-pump inhibitors.

Measure	Baseline	6–12 years	p
	n = 124	n = 91
Total time (%)
pH < 4	9.7 (6.4)	4.2 (4.9)	< 0.001
Upright	9.7 (7.8)	4.6 (4.9)	< 0.001
Supine	8.3 (9.6)	3.3 (7.4)	< 0.001
Reflux episodes
Total number	92.2 (92.2)	71.5 (67.7)	0.125
Number lasting > 5 min	6.1 (6.0)	4.3 (5.8)	0.036
Longest (minutes)	32.9 (34.2)	19.6 (31.5)	0.005
DeMeester score	40.7 (26.5)	16.3 (18.8)	< 0.001