Table 2.
Comparison of HLA class I and class II allele frequencies in NMO patients and controls.
| HLA Allele | NMO (n = 71) | Controls (n = 97) | P | |||
|---|---|---|---|---|---|---|
| AF | n | AF | n | |||
| Protective | B*39:05 | 0.0423 | 6 | 0.0979 | 19 | 0.04088 |
| DRB1*07:01 | 0.0282 | 4 | 0.0876 | 17 | 0.01996 | |
| DRB1*04:07 | 0.0775 | 11 | 0.1598 | 31 | 0.01692 | |
| DQB1*02:02 | 0.0282 | 4 | 0.0979 | 19 | 0.00899 | |
| DQB1*03:02 | 0.1197 | 17 | 0.2887 | 56 | 0.00013 | |
| Risk | B*39:06 | 0.0775 | 11 | 0.0309 | 6 | 0.04818 |
| B*35:14 | 0.0493 | 7 | 0.0103 | 2 | 0.03275 | |
| DQB1*04:02 | 0.2746 | 39 | 0.1546 | 30 | 0.00552 | |
| DRB1*14:06 | 0.0915 | 13 | 0.0206 | 4 | 0.00368 | |
| DRB1*16:02 | 0.1549 | 22 | 0.0515 | 10 | 0.00140 | |
| DRB1*08:02 | 0.2676 | 38 | 0.1289 | 25 | 0.00110 | |
| DQB1*03:01 | 0.3380 | 48 | 0.1546 | 30 | 0.00008 | |
AF, Allele frequency. Only alleles with a frequency ≥ 0.01 in both groups and with significant differences between cases and controls are presented.