Table 3.
Comparison of HLA class I and class II haplotype frequencies in NMO patients and controls.
| HLA Haplotype | NMO (n = 71) | Controls (n = 97) | P | |||||
|---|---|---|---|---|---|---|---|---|
| HF | n | Δ′ | HF | n | Δ′ | |||
| Protective | B*39:05-C*07:02 | 0.0423 | 6 | 1 | 0.0979 | 19 | 1 | 0.04088 |
| DRB1*04:07-DQB1*03:02 | 0.0704 | 10 | 0.8967 | 0.1546 | 30 | 1 | 0.01300 | |
| DRB1*07:01-DQB1*02:02 | 0.0211 | 3 | 0.7428 | 0.0876 | 17 | 1 | 0.00796 | |
| Risk | B*35:14-C*04:01 | 0.0493 | 7 | 1 | 0.0103 | 2 | 1 | 0.03275 |
| B*39:06-C*07:02 | 0.0704 | 10 | 0.8805 | 0.0206 | 4 | 1 | 0.02422 | |
| DRB1*14:06-DQB1*03:01 | 0.0915 | 13 | 1 | 0.0206 | 4 | 1 | 0.00368 | |
| DRB1*08:02-DQB1*04:02 | 0.2606 | 37 | 0.9637 | 0.1289 | 25 | 1 | 0.00177 | |
| DRB1*16:02-DQB1*03:01 | 0.1549 | 22 | 1 | 0.0515 | 10 | 1 | 0.00140 | |
HF, Haplotype frequency. Only haplotypes with a frequency ≥ 0.01 in both groups and with significant differences between cases and controls are presented.