FIGURE 1.

Overview of all antibody fragments analyzed with the available PDB accession codes crystallized with and without antigen and in the naive and matured state. Additionally, the resulting number of clusters of the CDR-H3 loop of the naïve and matured antibody fragments by using the same distance cut-off of 1.2 Å is shown on the left and visualized on the right. The plot on the right shows the number of clusters of the naïve antibody against the number of clusters of the matured antibody color-coded according to their loop length.