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In vivo regeneration of rat cranial defects: (a) schematic illustration of cryogenic 3D printed dual delivery scaffolds for cranial defect mouse treatment model; (b) typical μ-CT images of regenerated cranial bone defects; (c) bone volume/total volume (BV/TV) ratio of regenerated tissue; (d) bone mineral density of regenerated bone tissue. Control group refers to non-treatment of the rat bone defect.
