Table 6.

Treatment Used for Pandemic Diseases.^*

Disease	Treatment
Smallpox	Tecovirimat†
Measles	Vitamin A
Plague	Doxycycline‡
Cholera	Massive rehydration; doxycycline (in adults)‡; azithromycin (in children)‡
Yellow fever	None
Influenza H1N1	Oseltamivir§
Influenza H3N2	Oseltamivir§
Influenza H2N2	Oseltamivir§
AIDS	>20 antiviral drugs grouped in 8 classes and >40 combinations of two or more drugs
SARS	None
Ebola	REGN-EB3**
MERS	None
COVID-19	Remdesivir††

^*Only approved drugs are included.

^†Never used in humans. Two million doses stockpiled in the US, in case of bioterror attack.

^‡Other effective antibiotics available.

^§Other effective antivirals available.

^**Includes three types of antibodies.

^††Several other antivirals under investigation.

AIDS, acquired immune deficiency syndrome; COVID-19, coronavirus disease 2019; H1N1, hemagglutinin-1 neuraminidase-1; H2N2, hemagglutinin-2 neuraminidase-2; H3N2, hemagglutinin-3 neuraminidase-2; MERS, Middle East respiratory syndrome; SARS, severe acute respiratory syndrome.