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Gene regulations were different between VCP TG and WT mice in response to TAC during the development of heart failure. Hierarchical clustering analysis (A–B) and GO functional analysis of DEGs (C–D) based on the comparison of 5 weeks (5 W) TAC vs sham in either WT (A and C) or VCP TG mice (B and D). CC: the cellular components; MF: the molecular function; and BP: biological process according to p-value. N = 3–4 mice/group.
