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VCP exhibits a different regulation on the transcription factors by an Ingenuity Pathway Analysis (IPA). A. Il10-ra-mediated downstream genes were inhibited in WT TAC mice as compared to their sham controls. B.Rictor was activated in VCP TG mice upon 5 W TAC, resulting in the repression of the downstream genes related to the oxidative stress. N = 3–4 mice/group.
