FIGURE 6.

Deviation in volume from age norm and prediction error. (a) Graphs of five ROIs, detected with the current inference scheme, showing the correlation between the age‐controlled volume and the signed prediction error. Age‐normalized volume was computed by regressing out subjects chronological age from the measured volume. Volume was determined according to the Desikan‐Killiany atlas fitted with Freesurfer. Prediction error was formulated as the chronological age minus the predicted age. Note that for the sake of brevity, in the upper five plots, the volume of the lateral ventricles and choroid plexus was computed as the sum of their subparcellations. (b) The bar graph depicts the correlation between the age normalized volume and the signed prediction error for all the 98 regions in the parcellation. Positive correlations are presented in blue and negative in orange for simple magnitude comparison. As shown, the age‐controlled volume of cavities containing CSF and the choroid plexus (L/R Lateral Ventricle, L/R inferior Lateral Ventricle, 3rd ventricle, nonventricles CSF, L/R choroid plexus), except for the 4th ventricle, had the largest correlation with the model's prediction error compared with all other WM/GM regions (see Figure S6 for the full labels)