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. 2020 Aug 13;10:13697. doi: 10.1038/s41598-020-70763-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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p53 jumped along DNA. (A) Typical kymographs of p53 demonstrating traces showing jumps along DNA obtained in the presence of different salt concentrations. Arrows denote the identified jumps. (B) Distribution of the jump distance of p53 observed in 150 mM KCl. (C) Distribution of the jump time of p53 observed in 150 mM KCl. (D) Distribution of the jump velocity of p53 observed in 150 mM KCl. (E) Salt-concentration dependence of the average jump frequency of p53. Errors denote the standard errors calculated from at least three measurements. The jump frequencies in 130, 135, 145, and 150 mM KCl were statistically different from that in 50 mM KCl (p < 0.05, two-tailed t test).