Figure 4.
Circ-CDYL regulates miR-1180/YAP axis in MM cells. (a) The luciferase activity of MM cells co-transfected with wild-type or mutant YAP 3ʹ-UTR reporter and control or miR-1180 mimics. (b) qRT-PCR analysis of YAP mRNA expression in MM cells transfected with miR-1180 mimics or inhibitors. (c, d) qRT-PCR and Western blot analysis of YAP expression in circ-CDYL-silenced MM cells transfected with miR-1180 inhibitors. (e–g) The CCK-8, EdU, and apoptosis assays in circ-CDYL-silenced MM cells transfected with miR-1180 inhibitors. *P < 0.05, **P < 0.01.
