Table 1.

MC4R mutations identified in this study.

Site	Region	Amino acid change	Frequency
NC_000018.10:g.60371817G>A	Coding; TM	T187M	1/27
NC_000018.10:g.60371854C>T	Coding; TM	V166I	1/27
NC_000018.10:g.60372043C>T	Coding; TM	V103I	1/27
NC_000018.10:g.60372565G>A	5'-UTR	None	4/27

TM: transmembrane region; T: threonine; M: methionine; V: valine; I: isoleucine; UTR: untranslated region.