TABLE 1.
Associations of TESC expression and the clinicopathological features of 172 HCC patients
| Feature | TESC expression | P value | |
|---|---|---|---|
| Low | High | ||
| Total (cases) | 111 | 61 | |
| Age [years, median (range)] | 51 (20‐75) | 49 (34‐72) | 0.787 |
| Gender [cases (%)] | 0.583 | ||
| Male | 99 (89.2) | 56 (91.8) | |
| Female | 12 (10.8) | 5 (8.2) | |
| HBV infection [cases (%)] | 0.481 | ||
| Yes | 96 (86.5) | 55 (90.2) | |
| No | 15 (13.5) | 6 (9.8) | |
| Tumor number [cases (%)] | 0.925 | ||
| Single | 79 (71.2) | 43 (70.5) | |
| Multiple | 32 (28.8) | 18 (29.5) | |
| Tumor size [cases (%)] | 0.011 | ||
| ≤5 cm | 51 (45.9) | 16 (26.2) | |
| > 5 cm | 60 (54.1) | 45 (73.8) | |
| Macrovascular invasion [cases (%)] | 0.200 | ||
| Yes | 5 (4.5) | 6 (9.8) | |
| No | 106 (95.5) | 55 (90.2) | |
| Cirrhosis [cases (%)] | 0.801 | ||
| Yes | 55 (49.5) | 29 (47.5) | |
| No | 56 (50.5) | 32 (52.5) | |
| Clinical TNM stage [cases (%)] | 0.322 | ||
| I | 72 (64.9) | 35 (57.4) | |
| II | 13 (11.7) | 8 (13.1) | |
| III | 26 (23.4) | 18 (29.5) | |
| Differentiation grade [cases (%)] | 0.753 | ||
| I+II | 61 (55.0) | 32 (52.5) | |
| III+IV | 50 (45.0) | 29 (47.5) | |
| AFP [cases (%)] | 0.252 | ||
| ≤400 ng/mL | 61 (55.0) | 39 (63.9) | |
| > 400 ng/mL | 50 (45.0) | 22 (36.1) | |
| Postoperative TACE [cases (%)] | 0.029 | ||
| Yes | 13 (11.7) | 15 (24.6) | |
| No | 98 (88.3) | 46 (75.4) | |
| White blood cells (× 109/L, mean ± SD) | 6.53 ± 1.61 | 7.02 ± 2.32 | 0.105 |
| Platelet count (× 109/L, mean ± SD) | 196.86 ± 83.25 | 191.57 ± 82.05 | 0.692 |
| Hemoglobin (g/L, mean ± SD) | 143.39 ± 16.75 | 140.32 ± 15.62 | 0.243 |
| Serum ALT level (U/L, mean ± SD) | 42.08 ± 26.66 | 46.73 ± 32.61 | 0.314 |
| Total bilirubin (μmol/L, mean ± SD) | 41.13 ± 20.17 | 51.63 ± 37.73 | 0.018 |
| Serum AST level (U/L, mean ± SD) | 15.80 ± 5.51 | 14.39 ± 4.95 | 0.098 |
| Albumin (g/L, mean ± SD) | 42.81 ± 3.95 | 41.71 ± 4.12 | 0.086 |
| Prothrombin time (s, mean ± SD) | 12.55 ± 1.38 | 12.43 ± 1.36 | 0.588 |
TESC: Tescalcin; HCC: hepatocellular carcinoma; HBV: hepatitis B virus; AFP: alpha‐fetoprotein; TACE: transarterial chemoembolization; SD: standard deviation; ALT: alanine aminotransferase; AST: aspartate aminotransferase.