Table 2.
Estimated Statistically Significant Effects on HRQoL and Associated Health State Values From Clinical Events (High-risk Patients Only)
| Variable | Estimated HRQoL Decrementa | Estimated Health State Valuea |
|---|---|---|
| No event | NA | 0.84606 (0.83292 to 0.85921) |
| NMIBC recurrence (grade 3) | −0.08306b (−0.13379 to −0.03233) | 0.76300 (0.71178 to 0.81422) |
| MIBC progression | −0.09909b (−0.17256 to −0.02561) | 0.74698 (0.67309 to 0.82087) |
Data presented as mean (95% confidence interval).
Abbreviations: HRQoL = health-related quality of life; MIBC = muscle-invasive bladder cancer; NA = not applicable; NMIBC = non–muscle-invasive bladder cancer.
a
Multivariate HRQoL longitudinal model controlled for baseline EQ-5D score, treatment (celecoxib), patient characteristics, bladder cancer history, annual time dummies, and events.
b
P < .01.