Supplemental Table 11.
Costing Regression
| Total Costs | Coefficient | SE | z | P > z | 95% CI |
|---|---|---|---|---|---|
| Tumor recurrence | |||||
| Unknown | 1517.223 | 1729.041 | 0.88 | .380 | −1871.636 to 4906.082 |
| Grade 1 | 1217.438 | 415.9633 | 2.93 | .003 | 402.1653 to 2032.711 |
| Grade 2 | 1676.051 | 385.9831 | 4.34 | .000 | 919.5377 to 2432.564 |
| Grade 3 | 3956.667 | 829.3751 | 4.77 | .000 | 2331.122 to 5582.212 |
| Risk group, high risk | 1967.914 | 311.494 | 6.32 | .000 | 1357.397 to 2578.431 |
| Year | |||||
| 2 | −921.3536 | 251.7046 | −3.66 | .000 | −1414.686 to −428.0217 |
| 3 | −1514.189 | 233.9928 | −6.47 | .000 | −1972.806 to −1055.571 |
| Risk group & year | |||||
| High risk & year 2 | −1511.85 | 343.8087 | −4.40 | .000 | −2185.702 to −837.997 |
| High risk & year 3 | −1894.898 | 319.9745 | −5.92 | .000 | −2522.036 to −1267.759 |
| Progression | 5406.938 | 1400.335 | 3.86 | .000 | 2662.332 to 8151.544 |
| Progression history | 2269.138 | 806.8528 | 2.81 | .005 | 687.7356 to 3850.54 |
| TCC history | 91.53518 | 91.50393 | 1.00 | .317 | −87.80923 to 270.8796 |
| Patient gender | 162.3912 | 104.348 | 1.56 | .120 | −42.12716 to 366.9096 |
| Diabetes | −67.09895 | 147.0358 | −0.46 | .648 | −355.2838 to 221.0859 |
| Celecoxib treatment | −103.1504 | 90.55783 | −1.14 | .255 | −280.6405 to 74.33965 |
| Toxicity | |||||
| Mild condition | 190.4007 | 173.7812 | 1.10 | .273 | −150.2041 to 531.0055 |
| Moderate condition | 171.735 | 300.5923 | 0.57 | .568 | −417.415 to 760.885 |
| Celecoxib treatment & toxicity interaction | |||||
| Interaction | |||||
| 1 & Mild condition | 153.2397 | 242.295 | 0.63 | .527 | −321.6498 to 628.1292 |
| 1 & Moderate condition | 390.0575 | 387.7738 | 1.01 | .314 | −369.9651 to 1150.08 |
| Age, y | |||||
| 50-59 | 36.85634 | 193.8437 | 0.19 | .849 | −343.0704 to 416.7831 |
| 60-69 | 62.7073 | 177.3931 | 0.35 | .724 | −284.9767 to 410.3913 |
| 70-79 | −78.92821 | 182.5277 | −0.43 | .665 | −436.676 to 278.8195 |
| >80 | 59.02592 | 226.9982 | 0.26 | .795 | −385.8824 to 503.9342 |
| BMI | |||||
| Overweight | 207.6795 | 95.78029 | 2.17 | .030 | 19.95362 to 395.4054 |
| Obese | 258.0722 | 113.3226 | 2.28 | .023 | 35.96402 to 480.1804 |
| Morbidly obese | 1257.968 | 623.3053 | 2.02 | .044 | 36.31178 to 2479.624 |
| Smoking status | |||||
| Previous | −57.20011 | 97.19538 | −0.59 | .556 | −247.6996 to 133.2993 |
| Current | −241.9663 | 122.4042 | −1.98 | .048 | −481.8741 to −2.058529 |
| Constant | 2348.796 | 305.0676 | 7.70 | .000 | 1750.875 to 2946.718 |
Abbreviations: BMI = body mass index; CI = confidence interval; SE = standard error; TCC = transitional cell carcinoma.