Table 5.
Summary of Bacterial Cultures of Spontaneous Sputum Samples
| Ciprofloxacin [n (%)] | Placebo [n (%)] | |
|---|---|---|
| Baseline | ||
| Number of patients with a sputum sample | 25 (34.7) | 22 (30.5) |
| Number of bacterial cultures positive for a pathogen | 15 (20.8) | 12 (16.6) |
| H. influenzae | 6 (8.3) | 4 (5.5) |
| S. pneumoniae | 1 (1.4) | 2 (2.8) |
| P. aeruginosa | 2 (2.8) | 3 (4.2) |
| M. catarrhalis | 3 (4.2) | 1 (1.4) |
| S. aureus | 0 | 1 (1.4) |
| Other gram-negative bacteria | 3 (4.2) | 1 (1.4) |
| Cultures with ciprofloxacin-resistant bacteria | 1 (1.4) | 0 |
| Day 90 | ||
| Number of patients with a sputum sample | 16 (22.2) | 17 (23.6) |
| Number of patients with bacterial culture positive for a pathogen | 7 (9.7) | 7 (9.7) |
| Number of patients with newly acquired ciprofloxacin resistance | 0 | 1 (1.4) |
Definition of abbreviations: H. influenzae = Haemophilus influenzae; M. catarrhalis = Moraxella catarrhalis; P. aeruginosa = Pseudomonas aeruginosa; S. aureus = Staphylococcus aureus; S. pneumoniae = Streptococcus pneumoniae.