Table 1.
Baseline Features of the Study Population Presented as a Whole or as NIV Outcome at 24 Hours
| Feature | Overall | NIV Failure | NIV Success | P Value |
|---|---|---|---|---|
| Number of patients | 30 | 12 | 18 | — |
| Age, yr | 71 (66–81) | 69 (62–80) | 71 (68–81) | 0.7 |
| Sex, M | 20 (67) | 8 (67) | 12 (67) | >0.9 |
| BMI, kg/m2 | 23 (19–27) | 22.5 (18–26) | 24 (21–27) | 0.3 |
| Charlson index score | 4 (3–5.5) | 4 (3–5) | 4.5 (3–6) | 0.6 |
| Pneumonia | 13 (23) | 5 (42) | 8 (44) | >0.9 |
| ARDS | 15 (50) | 7 (58) | 8 (44) | 0.7 |
| Kelly scale score | 1 (1–1) | 1 (1–1) | 1 (1–1) | 0.4 |
| APACHE II score | 27 (21–38) | 24.5 (19–45) | 28 (25–37) | 0.8 |
| SAPS II score | 36 (26–41) | 36 (31–38) | 36 (25–44) | 0.6 |
| SOFA score | 6 (4–8.8) | 5.5 (3–8) | 6.5 (4–9) | 0.6 |
| PaO2/FiO2 ratio, mm Hg | 125 (101–170) | 118 (100–141) | 133 (111–144) | 0.5 |
| pH | 7.48 (7.44–7.51) | 7.49 (7.46–7.52) | 7.48 (7.44–7.5) | 0.2 |
| PaCO2, mm Hg | 35 (30–40) | 34 (30–37) | 36 (30–42) | 0.2 |
| Blood lactate, mg/dl | 27 (14–40) | 30 (18–40) | 25 (12–40) | 0.7 |
| Serum creatinine, mg/dl | 0.68 (0.5–0.9) | 0.6 (0.5–0.7) | 0.8 (0.65–0.8) | 0.4 |
| PEEP, cm H2O | 8 (6.5–10) | 8 (7.5–10) | 8 (6–10) | 0.7 |
| PS, cm H2O | 10 (10–14) | 11 (10–12) | 11 (10–14) | 0.3 |
Definition of abbreviations: APACHE II = Acute Physiology and Chronic Health Evaluation II; ARDS = acute respiratory distress syndrome; BMI = body mass index; NIV = noninvasive mechanical ventilation; PEEP = positive end-expiratory pressure; PS = pressure support; SAPS II = Simplified Acute Physiology Score; SOFA = Subsequent Organ Failure Assessment.
Data are presented as n (%) for dichotomous values or median (interquartile range) for continuous values unless otherwise specified.