Table 3.
Association between Physiological and Clinical Variables and NIV Failure at 24 Hours
| Feature | OR | 95% CI | P Value |
|---|---|---|---|
| ΔPes < 10 cm H2O post 2 h NIV | 15 | 2.8–110 | 0.001 |
| Vte > 9.5 ml/kg of PBW | 7.9 | 1.5–72 | 0.02 |
| HACOR score >5 post 2 h NIV | 6.3 | 0.9–49 | 0.046 |
| RR > 30 bpm | 5.5 | 0.8–112 | 0.14 |
| PaO2/FiO2 ratio < 150 mm Hg | 2 | 0.5–9.8 | 0.4 |
| Vte/ΔPl ratio < 0.33 ml/kg/cm H2O | 2 | 0.4–9.8 | 0.36 |
Definition of abbreviations: bpm = breaths/min; CI = confidence interval; ΔPes = tidal change in esophageal pressure; ΔPl = tidal change in dynamic transpulmonary pressure; HACOR = Heart Rate, Acidosis, Consciousness, Oxygenation and Respiratory Rate; NIV = noninvasive mechanical ventilation; OR = odds ratio; PBW = predicted body weight; RR = respiratory rate; Vte = expiratory Vt.