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. 2020 Aug 7;11:1197. doi: 10.3389/fphar.2020.01197

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Copyright © 2020 Yi, Xu, Huang, Zhang, Qing, Li, Wang, Zeng, Lu and Han

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TPPU inhibited expression of inflammatory factors and apoptosis in the OGD/R model. (A) Western blotting images. (B–F) Densitometric analysis of protein bands (n = 6). GAPDH served as the loading control. ^# P < 0.01 vs. control group; *P < 0.05, **P < 0.01 vs. OGD/R group. TPPU, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea; GAPDH, glyceraldehyde-3-phosphate; OGD/R, oxygen-glucose deprivation/reperfusion; IL-1β, interleukin-1β; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; PDTC, pyrrolidinedithiocarbamate.