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. Author manuscript; available in PMC: 2020 Aug 14.
Published in final edited form as: Nat Protoc. 2020 Feb 12;15(3):750–772. doi: 10.1038/s41596-019-0247-2

Fig. 10 |. Lineages reconstructed from a reprogramming time course.

Fig. 10 |

a, Force-directed graph of clonally related cells and lineages reconstructed from a reprogramming time course (1,031 clones, 12,932 cells). All lineages and clone distributions can be interactively explored using our companion website, CellTag Viz (http://www.celltag.org/). b, A detailed example of a lineage tree, where we follow a CellTagV1-labeled clone (cells labeled as MEFs, at day 0) and its descendants. Each node represents an individual cell, and edges represent clonal relationships between cells. Purple, CellTagV1 clones; blue, CellTagV2 clones (cells labeled at day 3, after reprogramming initiation); yellow, CellTagV3 clones (cells labeled at day 13, after reprogramming initiation).