TABLE 1.
Univariate analysis |
Multivariate analysis |
||||
Variable | N | P-value | HR (95% CI) | P-value | HR (95% CI) |
Histological subtype | |||||
Epithelial | 23 | 0.038 | 2.232 (1.047–4.759) | 0.717 | 0.834 (0.312–2.226) |
Mixed | 16 | ||||
Node status | |||||
N0 | 8 | 0.045 | 2.945 (1.025–8.461) | 0.089 | 3.060 (0.843–11.106) |
N + | 31 | ||||
Margins | |||||
Negative | 5 | 0.347 | 1.771 (0.538–5.832) | 0.179 | 2.703 (0.634–11.529) |
Positive | 34 | ||||
Brigham stage | |||||
Stage1 + 2 | 12 | 0.394 | 1.404 (0.644–3.064) | 0.628 | 0.784 (0.292–2.101) |
Stage3 + 4 | 27 | ||||
Risk score | |||||
Low-risk | 20 | <0.0001 | 4.963 (2.190–11.247) | <0.001 | 5.995 (2.178–16.502) |
High-risk | 19 |
N, number; HR, hazard ratio; CI, confidence interval. *One patient was not included in the univariate and multivariate analysis of the GSE2549 dataset, as the clinical information was not available. All P values in bold were less than 0.05 which were considered statistically significant.