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. 2020 Aug 7;11:899. doi: 10.3389/fgene.2020.00899

TABLE 1.

Univariate and multivariate survival analysis of GSE2549.

Univariate analysis
Multivariate analysis
Variable N P-value HR (95% CI) P-value HR (95% CI)
Histological subtype
Epithelial 23 0.038 2.232 (1.047–4.759) 0.717 0.834 (0.312–2.226)
Mixed 16
Node status
N0 8 0.045 2.945 (1.025–8.461) 0.089 3.060 (0.843–11.106)
N + 31
Margins
Negative 5 0.347 1.771 (0.538–5.832) 0.179 2.703 (0.634–11.529)
Positive 34
Brigham stage
Stage1 + 2 12 0.394 1.404 (0.644–3.064) 0.628 0.784 (0.292–2.101)
Stage3 + 4 27
Risk score
Low-risk 20 <0.0001 4.963 (2.190–11.247) <0.001 5.995 (2.178–16.502)
High-risk 19

N, number; HR, hazard ratio; CI, confidence interval. *One patient was not included in the univariate and multivariate analysis of the GSE2549 dataset, as the clinical information was not available. All P values in bold were less than 0.05 which were considered statistically significant.