TABLE 2.
Univariate analysis |
Multivariate analysis |
||||
Variable | N | P-value | HR (95% CI) | P-value | HR (95% CI) |
Gender | |||||
Female | 11 | 0.302 | 0.690 (0.340–1.397) | 0.011 | 0.354 (0.159–0.785) |
Male | 45 | ||||
Race | |||||
Asian | 1 | 0.518 | 0.719 (0.264–1.958) | 0.924 | 0.948 (0.317–2.836) |
White | 55 | ||||
AJCC stage | |||||
I + II | 18 | 0.621 | 0.850 (0.447–1.617) | 0.311 | 1.942 (0.538–7.017) |
III + IV | 38 | ||||
T stage | |||||
T1 + T2 | 28 | 0.455 | 0.798 (0.441–1.444) | 0.179 | 0.488 (0.171–1.389) |
T3 + T4 | 28 | ||||
N stage | |||||
N0 | 33 | 0.171 | 0.648 (0.349–1.206) | 0.116 | 0.493 (0.204–1.190) |
N + | 23 | ||||
M stage | |||||
M0 | 53 | 0.387 | 1.888 (0.447–7.983) | 0.179 | 3.585 (0.556–23.106) |
M1 | 3 | ||||
Risk score | |||||
Low-risk | 26 | <0.0001 | 6.412 (2.806–14.625) | <0.0001 | 9.009 (3.644–22.274) |
High-risk | 30 |
N, number; HR, hazard ratio; CI, confidence interval; AJCC, American Joint Commission on Cancer. *Nineteen patients were not enrolled in the univariate and multivariate analysis of TCGA dataset, as some clinical information was not available. All P values in bold were less than 0.05 which were considered statistically significant.