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. 2020 Aug 7;11:899. doi: 10.3389/fgene.2020.00899

TABLE 2.

Univariate and multivariate survival analysis of TCGA.

Univariate analysis
Multivariate analysis
Variable N P-value HR (95% CI) P-value HR (95% CI)
Gender
Female 11 0.302 0.690 (0.340–1.397) 0.011 0.354 (0.159–0.785)
Male 45
Race
Asian 1 0.518 0.719 (0.264–1.958) 0.924 0.948 (0.317–2.836)
White 55
AJCC stage
I + II 18 0.621 0.850 (0.447–1.617) 0.311 1.942 (0.538–7.017)
III + IV 38
T stage
T1 + T2 28 0.455 0.798 (0.441–1.444) 0.179 0.488 (0.171–1.389)
T3 + T4 28
N stage
N0 33 0.171 0.648 (0.349–1.206) 0.116 0.493 (0.204–1.190)
N + 23
M stage
M0 53 0.387 1.888 (0.447–7.983) 0.179 3.585 (0.556–23.106)
M1 3
Risk score
Low-risk 26 <0.0001 6.412 (2.806–14.625) <0.0001 9.009 (3.644–22.274)
High-risk 30

N, number; HR, hazard ratio; CI, confidence interval; AJCC, American Joint Commission on Cancer. *Nineteen patients were not enrolled in the univariate and multivariate analysis of TCGA dataset, as some clinical information was not available. All P values in bold were less than 0.05 which were considered statistically significant.