Figure 2. Management of vitamin D intoxication: The management of vitamin D toxicity can be categorized into three steps: 1) Stabilization and supportive therapy. In unstable patients, immediate resuscitative measures should be undertaken including intubation, administration of intravenous fluids, and transfer to an intensive care unit (ICU) as appropriate; 2) Correction of hypercalcemia takes advantage of several different classes of medications, including loop diuretics, bisphosphonates, glucocorticoids or calcitonin; 3) Other therapies to consider most commonly include renal replacement therapy (RRT) in severe cases.