Figure 1.

Study design, therapeutic device, and calibration postures. (A) The study included 3 in-clinic visits over 3 months with interim prescribed twice-daily home-use of therapy. (B) The wrist-worn device consisted of a stimulator, detachable band, and base station. The stimulator applied the stimulation pattern to the band and had an onboard triaxial accelerometer to measure tremor. The band contained two working electrodes positioned over the median and radial nerves and a counter-electrode positioned on the dorsal side of the wrist. The base station streamed accelerometer and usage data daily and charged the device. (C) Patients performed either a lateral or forward postural hold for device calibration and for tremor measurement pre- and post-stimulation.