Figure 2.

Co-primary endpoints assessed in-clinic showed improvement in TETRAS and BF-ADL. Average TETRAS dominant hand score (left, scale range 0–24) and BF-ADL dominant hand score (right, scale range 8 to 32) are shown pre- and post-stimulation conducted at each in-clinic visit. The co-primary TETRAS and BF-ADL endpoints—improvement from baseline (pre-stimulation rating at Visit 1) to study exit (post-stimulation rating at Visit 3)—were both met (n = 205). Therapeutic response was also significant within each visit for both TETRAS and BF-ADL, and the pre-stimulation tremor rating improved significantly over 3 months of use. Error bars represent ±1 SEM, and * indicates p < 0.0001.