Table 1.
Characteristics of included studies
| First Author | Year | City | Peptic ulcer |
H. pylori isolates |
Age Female/Male |
cagA | VacA genotypes | Ref | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| s1 | s2 | m1 | m2 | s1m1 | s1m2 | s2m1 | s2m2 | ||||||||
| Dabiri | 2017 | Tehran | 40 | 160 |
45.5 ± 1 81/79 |
26 | 24/109 | 16/51 | 12/48 | 28/112 | 4/30 | 20/79 | 8/18 | 8/33 | [29] |
| Salari | 2009 | Tehran | 50 | 50 |
45 21/29 |
NA | 50/50 | 0/0 | 31/31 | 19/19 | NA | NA | NA | NA | [30] |
| Salehi | 2011 | Tehran | 54 | 100 |
9 53/70 |
NA | 42/62 | 7/19 | 34/36 | 15/45 | NA | NA | NA | NA | [31] |
| Doosti | 2009 | Shahrekord | 150 | 178 |
NA NA |
NA | NA | NA | NA | NA | 24/38 | 56/96 | 0/7 | 3/39 | [32] |
| Nahaei | 2008 | Tabriz | 48 | 150 |
38.3 74/76 |
31 | 20/83 | 3/36 | 8/43 | 15/76 | 7/36 | 13/47 | 1/7 | 2/29 | [33] |
| Douraghi | 2010 | Tehran | 12 | 80 |
43.3 ± 1 56/60 |
NA | 7/61 | NA/19 | 3/26 | 9/54 | 8/26 | 12/35 | 0 | 8/19 | [34] |
| Alikhani | 2014 | Hamadan | 27 | 137 |
53 64/89 |
25 | 16/52 | 5/16 | 8/21 | 13/47 | 6/16 | 10/36 | 2/5 | 3/11 | [35] |
| Sarvestani | 2007 | Shiraz | 33 | 69 |
47.2 127/137 |
37 | NA | NA | NA | NA | 1/65 | 6/97 | 0/65 | NA | [36] |
| Salehi | 2009 | Rasht | 77 | 106 |
41 46/38 |
44 | 39/55 | 9/22 | 31/31 | 18/29 | NA | NA | NA | NA | [37] |
| Abdollahi | 2019 | Kerman | 6 | 120 |
38.2 98/93 |
4 | 6/45 | NA | 2/29 | 3/29 | NA | NA | NA | NA | [38] |
| Havaei | 2014 | Isfahan | 40 | 100 |
43 45/55 |
NA | 40/100 | NA | 21/51 | 19/49 | 21/51 | 19/49 | NA | NA | [39] |
| Ghotaslou | 2013 | Tabriz | 62 | 115 |
NA NA |
47 | 48/82 | 47/79 | 14/21 | 48/94 | 13/19 | 35/63 | 1/2 | 47/79 | [40] |
| Khodaii | 2010 | Tehran | 73 | 141 | 41.4 ± 6 99/58 | 56 | 57/97 | 16/43 | 32/47 | 41/93 | 16/29 | 37/64 | 6/14 | 14/33 | [41] |
| Dabiri | 2009 | Tehran | 13 | 124 |
44.3 65/59 |
6 | 8/50 | 5/24 | 6/22 | 7/52 | 2/15 | 6/35 | 4/7 | 1/17 | [42] |
| Khodaii | 2013 | Tehran | 83 | 157 |
41.1 58/99 |
56 | 57/97 | 16/43 | 32/47 | 41/93 | 16/29 | 37/64 | 6/14 | 14/33 | [43] |
| Rezaeian | 2012 | Jahrom | 38 | 164 |
47 58/79 |
34 | NA | NA | NA | NA | 18/63 | 12/73 | 1/6 | 7/22 | [44] |
| Sedaghat | 2014 | Kashan | 8 | 37 |
44.6 ± 1 123/99 |
4 | 4/20 | 3/13 | 1/9 | 6/23 | 0/6 | 4/15 | 1/2 | 2/8 | [45] |
| Rafeey | 2013 | Tabriz | 4 | 33 |
8.28 NA |
2 | 1/37 | 1/20 | 0/16 | 2/41 | NA | NA | NA | NA | [46] |
| Souod | 2013 | Jahrom | 38 | 201 |
47 ± 1 85/79 |
34 | 15/135 | 8/29 | 19/67 | 19/97 | 23/108 | 10/73 | 1/6 | 7/22 | [47] |
| Pajavand | 2015 | Kermanshah | 20 | 96 |
46 41/55 |
NA | 19/47 | 1/49 | 3/10 | 17/86 | NA | 16/38 | NA | 1/47 | [48] |
| Jafari | 2008 | Tehran | 19 | 96 |
48 ± 1 29/26 |
15 | 10/66 | 8/27 | 4/30 | 13/59 | 2/22 | 7/40 | 2/8 | 6/19 | [49] |
| Mohammadi | 2003 | Tehran | 29 | 132 |
37.6 65/67 |
NA | 23/93 | 4/36 | 8/42 | 17/74 | 6/35 | 14/43 | 0/4 | 3/31 | [50] |
| Falsafi | 2015 | Tehran | 34 | 172 |
9.5 ± 2 72/37 |
NA | NA | NA | NA | NA | 8/34 | 14/59 | 5/26 | 7/40 | [51] |
| Sarvestani | 2006 | Shiraz | 61 | 286 | 45.3 ± 1136/150 | 54 | NA | NA | NA | NA | 21/81 | 33/110 | NA | 11/73 | [52] |