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. Author manuscript; available in PMC: 2020 Aug 14.
Published in final edited form as: Cell Rep. 2020 Jul 21;32(3):107939. doi: 10.1016/j.celrep.2020.107939

Figure 4. Human Biogeography and Ecology from Neanderthal to Modern Humans.

Figure 4.

(A) Prevalence and distribution of Saccharibacteria groups from 16S rRNA gene hits within body site-specific assembled contigs from the Human Microbiome Project (16S rRNA gene > 300 bp hit cutoff, n = 1,100 assemblies).

(B) Total hit distributions across body sites (Figure S2 includes supporting oligotyping data for these groups and additional SR-1 and GN02 group distributions).

(C) Percentage of genome coverage from mapped metagenomic read sets to genome assemblies from this study and previously available G1 assemblies for Saccharibacteria groups from ancient Neanderthal dental calculus (48,000 years) through to modern body sites in health and disease. Neanderthal calculus from the best preserved Neanderthal, El Sidrón 1, which suffered from a dental abscess, is included, as well as SPYNEWWL8 9 (SPYI), which had extensive DNA damage (Table S7).