Table 5.
Variable | Olive Oil group (n = 22) | Canola Oil group (n = 20) | P c | ||||
---|---|---|---|---|---|---|---|
Baseline | 6-Week | Δ value b | Baseline | 6-Week | Δ value b | ||
TC (mg/dL) | 116.77 ± 25.15 | 124.36 ± 28.94 | 8.45 ± 17.67 | 136.25 ± 46.45 | 133.35 ± 47.54 | −2.90 ± 16.81 | 0.10 |
LDL-C (mg/dL) | 63.64 ± 13.72 | 67.36 ± 17.39 | 3.68 ± 11.27 | 74.65 ± 30.46 | 72.90 ± 28.98 | −1.75 ± 9.03 | 0.16 |
sd-LDL (mg/dL) | 24.14 ± 10.32 | 23.14 ± 11.18 | −0.91 ± 6.34 | 22.10 ± 7.51 | 21.00 ± 9.48 | − 1.10 ± 6.35 | 0.62 |
HDL-C (mg/dL) | 37.73 ± 7.92 | 39.50 ± 7.46 | 1.50 ± 5.80 | 42.90 ± 6.49 | 43.15 ± 8.33 | 0.35 ± 5.21 | 0.79 |
TC/HDL-C | 3.17 ± 0.47 | 3.25 ± 0.71 | 0.08 ± 0.39 | 3.06 ± 0.72 | 3.10 ± 0.83 | 0.03 ± 0.33 | 0.81 |
TG (mg/dL) | 112.73 ± 33.04 | 120.50 ± 61.38 | 7.63 ± 36.45 | 122.45 ± 31.94 | 126.05 ± 35.40 | 3.90 ± 20.92 | 0.32 |
Lp-PLA2 mass (ng/mL) |
5.66 ± 4.09 | 6.00 ± 4.51 | 0.34 ± 1.57 | 3.96 ± 2.45 | 2.99 ± 1.65 | − 0.97 ± 1.84 † | 0.008 |
Lp-PLA2 Activity (nmol/min/mL) | 0.022 ± 0.013 | 0.021 ± 0.017 | − 0.000 ± 0.008 | 0.012 ± 0.003 | 0.010 ± 0.004 | − 0.001 ± 0.002 | 0.74 |
IL-6 (pg/mL) | 21.95 ± 20.38 | 12.49 ± 13.70 | − 9.46 ± 9.46 † | 19.53 ± 10.52 | 18.62 ± 8.55 | −0.90 ± 6.80 | 0.008 |
C3 (g/L) | 199.32 ± 35.04 | 200.68 ± 33.63 | 1.36 ± 36.64 | 205.30 ± 44.46 | 223.50 ± 42.40 | 18.10 ± 49.00 | 0.08 |
C4 (g/L) | 38.82 ± 11.99 | 36.23 ± 9.48 | −2.59 ± 9.09 | 39.20 ± 9.03 | 34.60 ± 10.35 | −4.55 ± 12.43 | 0.52 |
C3/C4 | 5.56 ± 1.98 | 5.37 ± 2.08 | 0.23 ± 0.91 | 5.37 ± 2.08 | 6.36 ± 2.45 | 0.99 ± 2.53 | 0.27 |
a All values are Mean ± SD
b Change of parameter between 6-week and baseline (6-week minus baseline)
c The values for 6-week were analyzed using ANCOVA with baseline values as covariate
† Significantly different from baseline. Data were compared using Paired t-test
TC Total Cholesterol, LDL-C Low Density Lipoprotein-Cholesterol, sd-LDL Small Dense LDL, HDL High Density Lipoprotein-Cholesterol, TG Triglyceride, Lp-PLA2 Lipoprotein-Associated Phospholipase A2, IL-6 Interleukin-6, C3 Complement component 3, C4 Complement component 4