Table 3.
Plant | Pure compounds with antitubercular activity | Chemical class | MIC of pure compounds (μg/ml) | Author(s) |
---|---|---|---|---|
Zanthoxylum leprieurii | 2-hydroxy-1, 3-dimethoxy-10-methyl-9-acridone (1), 1-hydroxy-3-methoxy-10-methyl-9-acridone (2), 3-hydroxy-1, 5, 6-trimethoxy-9-acridone (3) | Acridone alkaloids | 1.5 (1), 0.2 (2), 0.4 (3); tested against H37Rv | [5] |
Warburgia ugandensis Sprague | Muzigadial (4), muzigadiolide (5), linoleic acid (6) | Sesquiterpenes | 64 (4), 128 (5), 16 (6); tested against M. smegmatis | [58, 85] |
Tetradenia riparia | 15- sandaracopimaradiene-7α, 18-dio1 (7) | Diterpenediol | 25–100 | [37] |
MIC minimum inhibitory concentration. No toxicity studies of the pure compounds were conducted.