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. 2020 Aug 14;11(8):618. doi: 10.1038/s41419-020-02855-6

Fig. 3. MiR-93 suppresses PTX-resistance and tumorigenesis of breast cancer in vivo.

Fig. 3

a The subcutaneous tumor model was built by Bads-200 cells with stable expression of NC/miR-93, with subsequent treatment of PBS/PTX. b The expression levels of miR-93 in transplanted tumor tissues (n = 5, respectively) were measured. c–e MiR-93 significantly reduced tumor volume and weight, especially in the group with combinational treatment of miR-93 and PTX. f Representative images of Bads-200 xenografts with H&E or Ki67 staining. Scale bars: (main) 200 μm, (inset) 50 μm. Bars indicate the mean ± SD of three independent replicates. g The quantification of Ki67. *P < 0.05, **P < 0.01, ****P < 0.0001.