Table 1.
Self-reported clinical manifestations.
| Clinical Manifestation | Granulomatosis with polyangiitis | Microscopic polyangiitis |
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Na | n (%) | Na | n (%) | Z score | P value | |||
| Rash | 698 | 401 (57.4) | 156 | 93 (59.6) | –0.50 | .62 | |||
| Weight loss | 690 | 400 (58.0) | 151 | 86 (57.0) | 0.23 | .82 | |||
| Fever | 588 | 325 (55.3) | 139 | 64 (46.0) | 1.96 | .05 | |||
| Joint | 688 | 549 (79.8) | 154 | 106 (68.8) | 2.96 | .003 | |||
| Ear, nose, and throat |
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Any | 723 | 641 (88.7) | 164 | 89 (54.3) | 10.42 | <.001 | ||
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Nasal/sinus symptoms | 723 | 600 (83.0) | 146 | 89 (61.0) | 5.99 | <.001 | ||
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Hearing loss | 666 | 322 (48.3) | 144 | 22 (15.3) | 7.28 | <.001 | ||
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Tracheal | 610 | 183 (30.0) | 133 | 13 (9.8) | 4.80 | <.001 | ||
| Pulmonary |
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Any | 734 | 523 (71.3) | 154 | 90 (58.4) | 3.13 | .002 | ||
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Alveolar hemorrhage | 700 | 282 (40.3) | 161 | 58 (36.0) | 1.00 | .32 | ||
| Renal |
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Any | 743 | 457 (61.5) | 163 | 135 (82.8) | –5.18 | <.001 | ||
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Dialysis | 721 | 73 (10.1) | 163 | 18 (11.0) | –0.35 | .73 | ||
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Renal transplant | 721 | 10 (1.4) | 164 | 7 (4.3) | –2.43 | .02 | ||
| Pulmonary–renal | 684 | 184 (26.9) | 161 | 47 (29.2) | –0.59 | .56 | |||
| Peripheral nerve | 654 | 411 (62.8) | 147 | 95 (64.6) | –0.40 | .69 | |||
| Gastrointestinal | 683 | 14 (2.0) | 147 | 4 (2.7) | –0.51 | .61 | |||
| Venous thromboembolism | 701 | 96 (13.7) | 154 | 21 (13.6) | 0.02 | .99 | |||
| Pericardial | 609 | 49 (8.0) | 132 | 6 (4.6) | 1.39 | .16 | |||
| Eye | 609 | 330 (54.2) | 151 | 51 (33.8) | 3.14 | .002 | |||
aThe number of patients who responded yes or no (unknown and blank responses were excluded).