Table 5. Associations of clinical presentations with MDR-TB among study participants in the Tigray Region, northern Ethiopia, July 2018 to August 2019.
| Variables | Non-MDR-TB (189), F (%) | MDR-TB (%) (38), F (%) | OR (95% Cl) | P-value | AOR (95% Cl) | P-value |
|---|---|---|---|---|---|---|
| TB history | ||||||
| No | 152 (80.4) | 20 (52.6) | 1 | 1 | ||
| Yes | 37 (19.6) | 18 (47.4) | 3.7 (1.78–7.68) | 0.001 | 4.26 (1.99–9.14) | <0.001 |
| Duration of illness in days (198) | ||||||
| ≤60 | 104 (62.6) | 10 (31.3) | 1 | |||
| >60 | 62 (37.4) | 22 (68.7) | 3.69 (1.64–8.30) | 0.002 | - | - |
| Body mass index | ||||||
| >18.5 | 53 (28) | 8 (21) | 1 | |||
| ≤18.5 | 136 (72) | 30 (79) | 0.68 (0.29–1.59) | 0.377 | - | - |
| Weight loss | ||||||
| No | 18 (9.5) | 6 (15.8) | 1 | - | ||
| Yes | 171 (90.5) | 32 (84.2) | 0.56 (0.21–1.52) | 0.257 | - | |
| Chest pain | ||||||
| No | 57 (30.2) | 7 (18.4) | 1 | - | ||
| Yes | 132 (69.8) | 31 (81.6) | 1.91 (0.8–4.6) | 0.147 | - | |
| Coughing for > 2 weeks | ||||||
| No | 27 (14.3) | 6 (15.8) | 1 | |||
| Yes | 162 (85.7) | 32 (84.2) | 0.89 (0.34–2.33) | 0.810 | - | - |
| Shortness of breath | ||||||
| No | 92 (48.7) | 19 (50) | 1 | |||
| Yes | 97 (51.3) | 19 (50) | 0.95 (0.47–1.90) | 0.882 | - | - |
| Hemoptysis | ||||||
| No | 172 (91) | 33 (86.8) | 1 | |||
| Yes | 17 (9) | 5 (13.2) | 1.53 (0.53–4.44) | 0.431 | - | - |
| Intermittent fever | ||||||
| No | 119 (63) | 17 (44.7) | 1 | 1 | ||
| Yes | 70 (37) | 21 (55.3) | 2.1 (1.04–4.25) | 0.039 | 2.54 (1.21–5.4) | 0.014 |
| Night sweats | ||||||
| No | 44 (23.3) | 9 (23.7) | 1 | |||
| Yes | 145 (76.7) | 29 (76.3) | 0.98 (0.43–2.22) | 0.957 | - | - |
| Appetite loss | ||||||
| No | 68 (36) | 9 (23.7) | 1 | |||
| Yes | 121 (64) | 29 (76.3) | 1.81 (0.81–4.05) | 0.148 | - | - |
| Fatigue and malaise | ||||||
| No | 142 (75.1) | 30 (79) | 1 | |||
| Yes | 47 (24.9) | 8 (21) | 0.81 (0.35–1.88) | 0.617 | - | - |