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. 2020 Aug 4;16(8):e1008732. doi: 10.1371/journal.ppat.1008732

Fig 2. Analysis of VP6-specific polyclonal immune responses in mice and humans.

Fig 2

(A) Intracellular neutralisation of rotavirus infection by anti-DLP polyclonal serum versus control serum electroporated into cells. (B) Faecal antigen shedding as detected by ELISA on days 1–7 post infection in mice immunized with DLPs 2 and 4 weeks prior to infection, compared to naive mice (4–5 mice per group). (C) ELISAs to detect IgG and IgA polyclonal antibodies raised by DLP immunization in mice, each symbol representing one mouse. (D) Intracellular neutralisation of rotavirus (strain SA11) by VP6-specific IgG purified from human pooled IgG in MA104 cells. For all graphs, error bars represent standard error, **** p = < 0.0001, ** p = < 0.01, * p = < 0.05, NS not significant.