Fig 3. Production and characterization of VP6-specific recombinant monoclonal antibodies.
(A) Mouse-human chimeric 7D9 hIgG binds to DLPs by ELISA while control antibody (9C12) does not. (B) Mouse-human chimeric 7D9 hIgA binds to DLPs by ELISA. (C) Intracellular neutralisation of rotavirus by VP6-specific 7D9 with human IgG1 Fc region compared to IgA1 region electroporated into cells. For all graphs, error bars represent standard error, **** p = < 0.0001, *** p = < 0.001, ** p = < 0.01, * p = < 0.05, NS not significant.