Table 2. Top 50 uniquely up-regulated genes in tumor-derived TdTOSX+;CD45+ cells.
List of the 50 most highly expressed genes in the TdTOSX+;CD45+ cells compared to the TdTOSX-;CD45+ cells isolated from the TME.
| external_gene_ name |
description | TdTOSX+CD45+ logFC |
TdTOSX+CD45+ linearFC |
|---|---|---|---|
| Cd163l1 | CD163 molecule-like 1 | 6.482112 | 89.394369 |
| Ltb | lymphotoxin B | 6.217037 | 74.389998 |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 5.915697 | 60.367363 |
| Foxp3 | forkhead box P3 | 5.882423 | 58.991007 |
| Trbv19 | T cell receptor beta, variable 19 | 5.83901 | 57.242322 |
| Cd5 | CD5 antigen | 5.822965 | 56.609196 |
| Gm4759 | predicted gene 4759 | 5.712238 | 52.426999 |
| Tcrg-C1 | T cell receptor gamma, constant 1 | 5.709921 | 52.342868 |
| Icos | inducible T cell co-stimulator | 5.588856 | 48.129715 |
| Gm19585 | predicted gene, 19585 | 5.577582 | 47.755056 |
| Fasl | Fas ligand (TNF superfamily, member 6) | 5.571314 | 47.548033 |
| Rln3 | relaxin 3 | 5.518062 | 45.824955 |
| Ubash3a | ubiquitin associated and SH3 domain containing, A | 5.432308 | 43.180511 |
| Pcsk1 | proprotein convertase subtilisin/kexin type 1 | 5.376329 | 41.537117 |
| Ccr8 | chemokine (C-C motif) receptor 8 | 5.32423 | 40.06386 |
| Gimap3 | GTPase, IMAP family member 3 | 5.257508 | 38.253185 |
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 5.220641 | 37.288037 |
| Klrb1f | killer cell lectin-like receptor subfamily B member 1F | 5.204067 | 36.86212 |
| Ikzf3 | IKAROS family zinc finger 3 | 5.185332 | 36.386518 |
| Trdv4 | T cell receptor delta variable | 5.179288 | 36.234394 |
| Trat1 | T cell receptor associated transmembrane adaptor 1 | 5.144648 | 35.374755 |
| Pdcd1 | programmed cell death 1 | 5.092017 | 34.107504 |
| Izumo1r | IZUMO1 receptor, JUNO | 5.053635 | 33.212045 |
| Cd3e | CD3 antigen, epsilon polypeptide | 5.042174 | 32.949246 |
| Itk | IL2 inducible T cell kinase | 5.027182 | 32.608632 |
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 4.978043 | 31.516668 |
| Actn2 | actinin alpha 2 | 4.919967 | 30.27316 |
| Trbv1 | T cell receptor beta, variable 1 | 4.891164 | 29.674756 |
| Dkkl1 | dickkopf-like 1 | 4.820628 | 28.258804 |
| Cd300e | CD300E molecule | 4.801355 | 27.883791 |
| Pglyrp2 | peptidoglycan recognition protein 2 | 4.80032 | 27.863797 |
| Cd226 | CD226 antigen | 4.766441 | 27.21709 |
| Themis | thymocyte selection associated | 4.760082 | 27.097397 |
| Dpep3 | dipeptidase 3 | 4.694473 | 25.892693 |
| Cd209a | CD209a antigen | 4.650261 | 25.111233 |
| Cd27 | CD27 antigen | 4.648725 | 25.084512 |
| Gpr55 | G protein-coupled receptor 55 | 4.621113 | 24.608975 |
| Ccr6 | chemokine (C-C motif) receptor 6 | 4.596004 | 24.18439 |
| Gpr174 | G protein-coupled receptor 174 | 4.594683 | 24.16225 |
| A630023P12Rik | RIKEN cDNA A630023P12 gene | 4.586499 | 24.025577 |
| Cd28 | CD28 antigen | 4.564255 | 23.657981 |
| Cd3g | CD3 antigen, gamma polypeptide | 4.547609 | 23.386577 |
| Lta | lymphotoxin A | 4.534293 | 23.171712 |
| Ccr3 | chemokine (C-C motif) receptor 3 | 4.526527 | 23.047318 |
| Gzmb | granzyme B | 4.518658 | 22.921957 |
| Lrrc66 | leucine rich repeat containing 66 | 4.47147 | 22.184347 |
| Xirp2 | xin actin-binding repeat containing 2 | 4.462937 | 22.053513 |
| St8sia1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 4.460924 | 22.022769 |
| Sit1 | suppression inducing transmembrane adaptor 1 | 4.417363 | 21.367754 |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 4.381868 | 20.84844 |