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. 2020 Aug 14;6(33):eaba3546. doi: 10.1126/sciadv.aba3546

Fig. 3. Bacteria-triggered photothermal ablation of other tumor models.

Fig. 3

(A) Photographs of BALB/c mice bearing 4T1, U87MG, SW1990, and patient-derived xenografts (PDX) tumors, before and after injection of bacteria at the dose of 5 × 106 CFU. (B) Representative PA images of different types of tumors on mice injected with bacteria at the dose of 5 × 106 CFU. (C) Quantification of relative PA signals of tumors on mice injected with 5 × 106 CFU of bacteria. Data are presented as the mean ± SD. (D) Representative IR thermal images of the tumor-bearing mice injected with bacteria at the dose of 5 × 106 CFU under 808-nm laser irradiation. (E to H) Tumor growth curves of mice bearing different kinds of tumor models, including 4T1 tumors (E), U87MG tumors (F), SW1990 tumors, (G) and PDX tumors (H), with different treatments indicated. Five mice were used for each group. Data are presented as the mean ± SEM. Photo credit for (A): Xuan Yi, Soochow University.