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. 2020 Aug 14;6(33):eabb5093. doi: 10.1126/sciadv.abb5093

Fig. 4. Temporal delivery of exogenous BMP-2 induces early bone healing via an endochondral ossification process.

Fig. 4

(A) H&E- and Safranin O–stained sections of all groups after 2 weeks in vivo. Images were taken at 20×. DB denotes cartilage undergoing endochondral ossification to become developing bone, and B denotes positive new bone tissue. Quantification of the amount of (B) bone formation and (C) developing bone per total area. Error bars denote SDs (n = 9 animals). (D) μCT reconstructed images of the defect site.