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. 2020 Aug 12;6(5):e504. doi: 10.1212/NXG.0000000000000504

Figure. Patients with DM1 with variant repeats have milder symptoms in motor, neurocognitive, and behavioral domains.

Figure

Motor (A–C), cognitive (D–F), and behavioral (G–I) scores (y-axes) are shown across groups (x-axes), including controls, patients with DM1 with variant repeats, and patients with DM1 with pure repeats. There were significant differences in MIRS, FSIQ, processing speed, Beck Depression Inventory, and SCOPA-Sleep between the variant and pure repeat groups. Circles represent the mean value of each group (red = control group, green = variant repeat group, and blue = pure repeat group). The vertical, solid lines represent 95% confidence interval. The horizontal bars with asterisks (*) represent significant differences between groups. DM1 = myotonic dystrophy type 1; FSIQ = Full Scale IQ; MIRS = Muscle Impairment Rating Scale; SCOPA = Scales for Outcomes in Parkinson's Disease.