Table 3.
Difference in Competitive Luminex Immunoassay Geometric Mean Titers Between 24 and 120 Months Postvaccination as Estimated by a Linear Mixed Model
Girls | Women | ||||||||
---|---|---|---|---|---|---|---|---|---|
2D | 3D | 3D | |||||||
Log Difference (95% CI) | P Value | Log Difference (95% CI) | P Value | Log Difference (95% CI) | P Value | P Value for Difference of Differences, 2D Girls vs 3D Women | P Value for Difference of Differences, 3D Girls vs 3D Women | P Value for Difference of Differences, 2D Girls vs 3D Girls | |
HPV6 | 0.66 (0.39–0.93) | <.001 | 0.65 (0.51–0.78) | <.001 | 0.61 (0.32–0.91) | .002 | .90 | .94 | .92 |
HPV11 | 1.04 (0.89–1.19) | <.001 | 0.98 (0.81–1.15) | <.001 | 0.84 (0.48–1.20) | <.001 | .20 | .36 | .59 |
HPV16 | 0.81 (0.61–1.02) | <.001 | 0.95 (0.79–1.11) | <.001 | 0.82 (0.43–1.22) | .002 | .98 | .50 | .30 |
HPV18 | 0.93 (0.65–1.21) | <.001 | 1.11 (0.94–1.29) | <.001 | 0.90 (0.45–1.35) | .003 | .96 | .44 | .26 |
Abbreviations: 2D, 2 doses; 3D, 3 doses; CI, confidence interval; HPV, human papillomavirus.