Number of injection attempts and use of indwelling catheter, by age group, among all enrolled participants. Partial injection means that less than the full 0.5 mL of study product or normal saline placebo was injected intravenously; failed venous access means that no study product or normal saline placebo was injected intravenously. The order of the bar charts from left to right generally indicates the chronological order of study group enrollment (although the lowest dose group of the 13- to 59-month-olds were vaccinated at the same time as the highest dose group of the 5- to 9-year-olds, and the lowest dose group of the 5- to 12-month-olds was vaccinated at the same time as the 4.5 × 105 dose group of the 13- to 59-month-olds). Each dose group contains placebo and vaccine recipients. Abbreviations: DVI, direct venous inoculation; DVIc, direct venous inoculation using an intravenous cannula; 2+ DVI, 2 or more direct venous inoculations required; Vac 1, vaccine dose 1; Vac 2, vaccine dose 2.