TABLE 1.

Mean and standard error of hypothalamic total protein, albumin, malondialdehyde, total glucose, glycogen, lactate, pyruvate levels, and lactate/pyruvate ratio of male and female Sprague Dawley rats

	Male control	Male halo	Male cloz	Female control	Female halo	Female cloz
Protein level membrane
Hypothalamus (mg/ml)	9.08 ± 0.23	8.67 ± 0.14	8.74 ± 0.34	9.10 ± 0.31	8.86 ± 0.22	8.89 ± 0.33
Protein level cytosol
Hypothalamus (mg/ml)	9.17 ± 0.40	10.00 ± 0.35	9.11 ± 0.40	8.76 ± 0.33	8.49 ± 0.44	9.20 ± 0.46
Albumin
Hypothalamus (mg/ml)	9.14 ± 0.81	8.99 ± 0.59	7.3 ± 0.53	7.22 ± 0.60	7.39 ± 0.51	8.00 ± 0.54
Oxidative stress
Hypothalamus (MDAµmol/ml)	0.037 ± 0.007	0.029 ± 0.006	0.025 ± 0.006	0.034 ± 0.01	0.032 ± 0.01	0.034 ± 0.007
Fasting glucose
Serum (µg/ml)	47.46 ± 5.44	64.05 ± 4.58	57.22 ± 3.81	34.37 ± 1.59	40.33 ± 5.45	45.42 ± 2.99*
Total glucose
Hypothalamus (µg/ml)	8.70 ± 2.1	13.59 ± 3.2	7.89 ± 1.5	7.02 ± 1.2	8.85 ± 1.5	9.41 ± 1.9
Glycogen
Hypothalamus (µg/ml)	4.87 ± 0.52	4.38 ± 0.53	3.98 ± 0.75	5.24 ± 0.59	5.16 ± 0.91	5.41 ± 0.64
Lactate
Hypothalamus (mmol/L)	2.06 ± 0.072	2.14 ± 0.076	2.25 ± 0.085	2.05 ± 0.059	2.21 ± 0.072	2.31 ± 0.095*
Pyruvate
Hypothalamus (µmol/L)	64.64 ± 11.5	58.14 ± 7.1	47.71 ± 10.3	50.07 ± 12.02	41.93 ± 5.0	63.64 ± 13.8
Lactate/pyruvate ratio
Hypothalamus	40.95 ± 6.2	41.42 ± 4.8	70.04 ± 14.7	68.67 ± 16.9	59.23 ± 6.5	58.33 ± 17.3

cloz, clozapine medicated; halo, haloperidol medicated; with n _group = 10.

^* p < .05 and **p < .001 as significant.