Table 2.

Clinical comparison of PNS+ and PNS− pSS patients

Characteristics	PNS+, n = 23	PNS−, n = 27	p‐Value
Age (years, mean ± SD)	56.96 ± 11.38	54.81 ± 9.58	.323
First symptoms (year of life, mean ± SD)	45.83 ± 12.56	44.67 ± 11.17	.602
Diagnosis of pSS(year of life, mean ± SD)	53.52 ± 12.11	51.48 ± 11.01	.405
Time to diagnosis (years, mean ± SD)	7.7 ± 5.16	6.81 ± 7.2	.229
Disease duration (years, mean ± SD)	3.65 ± 3.42	3.78 ± 4.03	.938
Xerophthalmia	22 (96%)	27 (100%)	.273
Xerostomia	22 (96%)	27 (100%)	.273
Parotid enlargement	17 (74%)	12 (44%)	.035
Positive Schirmer test	17 (74%)	13 (48%)	.061
CNS involvement	7 (30%)	5 (19%)	.325
Vasculitis	7 (30%)	4 (15%)	.183
Articular involvement	12 (52%)	16 (59%)	.614
Gastrointestinal tract involvement	12 (52%)	14 (52%)	.981
Cardiovascular system involvement	2 (9%)	3 (11%)	.776
Respiratory tract involvement	15 (65%)	10 (37%)	.047
Lymphadenopathy	14 (61%)	5 (19%)	.002
Lymphoma	2 (9%)	0 (0%)	.073
Urinary tract involvement	12 (52%)	13 (48%)	.776
Autoimmune thyroid disease	2 (9%)	4 (15%)	.502
CNS involvement	7 (30%)	4 (15%)	.183
Cyclophosphamide treatment	4 (17%)	0 (0%)	.010
Steroid treatment	19 (83%)	18 (67%)	.194
ESSDAI (mean ± SD)	7 ± 6.82	4.7 ± 4.58	.245
ESSPRI (mean ± SD)	5.47 ± 1.66	4.82 ± 1.72	.187
SSDDI (mean ± SD)	4.65 ± 2.5	3.04 ± 2.1	.055
ODSS (mean ± SD)	1.78 ± 2.21	0.59 ± 0.93	.083

Abbreviations: CNS, central nervous system; ESSDAI EULAR, Sjögren's Syndrome Disease Activity Index; ESSPRI EULAR, Sjögren's Syndrome Patient Reported Index; ODSS, Overall Disability Sum Score; PNS−, patients without peripheral neuropathy; PNS+, patients with peripheral neuropathy; pSS, primary Sjögren's syndrome; SSDDI, Sjögren's Syndrome Disease Damage Index.

The results with statistical significance p<.05 are shown in bold.