Table 2.
Polysomnographic Parameters of Patients With HCM Grouped by the Presence of OSA or AHI Quartiles
| Variables | No OSA (n=228) | OSA (n=327) | P Value | Quartile 1 (n=138) AHI <2.0 events per h | Quartile 2 (n=139) AHI ≥2.0 to <7.5 events per h | Quartile 3 (n=139) AHI ≥7.5 to <18.8 events per h | Quartile 4 (n=139) AHI ≥18.8 events per h | P Value |
|---|---|---|---|---|---|---|---|---|
| AHI, events per h | 1.5 (0.6–2.9) | 16.6 (9.0–31.1) | <0.001 | 0.8 (0.3–1.4) | 4.3 (2.9–5.4) | 12.4 (9.2–15.5) | 33.7 (25.2–44.3) | <0.001 |
| OAI, events per h | 0.4 (0.1–1.0) | 5.0 (1.9–13.2) | <0.001 | 0.2 (0.0–0.5) | 1.0 (0.4–1.9) | 3.2 (1.1–6.0) | 16.2 (7.5–25.4) | <0.001 |
| CAI, events per h | 0.0 (0.0–0.0) | 0.0 (0.0–1.2) | <0.001 | 0.0 (0.0–0.0) | 0.0 (0.0–0.1) | 0.0 (0.0–0.8) | 0.4 (0.0–3.4) | <0.001 |
| Hypopnea index, events per h | 0.7 (0.2–1.8) | 8.0 (4.7–13.4) | <0.001 | 0.3 (0.1–0.7) | 2.5 (1.5–3.9) | 7.7 (5.1–10.2) | 12.3 (7.2–19.5) | <0.001 |
| ODI, events per h | 2.3 (1.0–4.3) | 16.4 (9.1–30.4) | <0.001 | 0.5 (1.5–2.3) | 4.9 (3.2–6.7) | 11.8 (9.1–15.9) | 33.0 (23.1–42.5) | <0.001 |
| Snoring time ratio, % | 3.0 (0.4–5.9) | 8.2 (2.3–15.4) | <0.001 | 2.0 (0.3–5.6) | 4.1 (0.4–9.7) | 7.3 (2.3–14.1) | 12.4 (3.8–22.0) | <0.001 |
| Longest apnea/hypopnea time, s | 36.7 (24.5–53.7) | 70.0 (53.5–91.7) | <0.001 | 27.2 (19.3–40.1) | 50 (40.0–73.5) | 65.3 (51.0–82.3) | 78.2 (58.0–95.0) | <0.001 |
| Lowest SaO2, % | 89.0 (86.0–90.0) | 82.0 (76.0–86.0) | <0.001 | 89.0 (87.0–91.0) | 87.0 (84.0–89.0) | 84 (80.0–86.0) | 78.0 (72.0–82.0) | <0.001 |
| Mean SaO2, % | 94.5 (94.0–95.5) | 93.2 (92.2–94.4) | <0.001 | 95.0 (94.1–95.7) | 94.0 (93.1–95.0) | 93.6 (92.8–94.6) | 93.0 (91.6–94.0) | <0.001 |
| Time spent with SaO2 <90%, % | 0.1 (0.0–1.5) | 5.3 (1.1–13.5) | <0.001 | 0.0 (0.0–1.0) | 0.5 (0.0–2.0) | 3.0 (0.9–8.3) | 12.1 (4.4–21.7) | <0.001 |
| Mean oxygen decline degree, % | 4.2 (3.8–4.7) | 5.5 (4.8–6.6) | <0.001 | 4.2 (3.8–4.7) | 4.4 (4.0–4.9) | 5.0 (4.8–5.7) | 6.5 (5.6–7.5) | <0.001 |
| HR during sleep | 60.1±7.2 | 61.3±7.5 | 0.001 | 58.9±6.5 | 61.2±7.3 | 60.7±7.0 | 62.3±8.5 | <0.001 |
| Supine time, min | 208.0 (168.8–269.3) | 208.0 (136.0–239.0) | 0.005 | 234.5 (181.0–312.3) | 208.0 (153.0–239.0) | 208.0 (137.0–254.0) | 206.0 (120.0–213.0) | <0.001 |
| Total recording time, min | 494.0 (420.0–540.0) | 451.0 (409.0–501.0) | <0.001 | 500.0 (439.3–551.5) | 473.0 (420.0–525.0) | 455.0 (414.0–512.0) | 434.0 (404.9–479.0) | <0.001 |
Values are presented as mean±SD, median (interquartile range), or number (percentage). AHI indicates apnea‐hypopnea index; CAI, central apnea index; HCM, hypertrophic cardiomyopathy; HR: heart rate; OAI, obstructive apnea index; ODI, oxygen desaturation index; OSA, obstructive sleep apnea; and SaO2, oxygen saturation.