Table 2.
Clinical Outcomes of Patients According to Quartile of Resistive Reserve Ratio
| Quartile 1 (RRR≥5) | Quartile 2 (RRR 3.5–4.9) | Quartile 3 (RRR 2.5–3.4) | Quartile 4 (RRR<2.5) | P Value | |
|---|---|---|---|---|---|
| Per‐patient analysis (n=1245) | 258 (20.7%) | 356 (28.6%) | 276 (22.2%) | 355 (28.5%) | |
| All‐cause death | 1.3% (3) | 2.7% (8) | 5.3% (10) | 6.6% (16) | 0.042 |
| Cardiac death | 0.9% (2) | 1.3% (4) | 2.2% (4) | 3.4% (8) | 0.338 |
| Myocardial infarction | 1.4% (3) | 2.3% (6) | 1.1% (2) | 4.1% (11) | 0.086 |
| Any revascularization | 8.8% (17) | 9.2% (26) | 12.6% (25) | 16.3% (42) | 0.029 |
| Target vessel‐related revascularizationa | 6.7% (11) | 5.8% (12) | 10.9% (15) | 13.8% (26) | 0.041 |
| Death or myocardial infarction | 2.2% (5) | 4.9% (14) | 6.0% (11) | 10.4% (27) | 0.003 |
| Patient‐oriented composite outcomeb | 9.9% (20) | 11.3% (33) | 17.2% (35) | 22.7% (61) | <0.001 |
Data expressed as cumulative incidence of clinical outcomes and numbers of events. Cumulative incidence of clinical outcomes represents Kaplan–Meier estimates during median follow‐up of 1422.0 days (Q1–Q3, 566.0–1855.0 days). P values for log‐rank or Breslow test in survival analysis. RRR indicates resistive reserve ratio.
a
Target vessel‐related revascularization denotes ischemia‐driven revascularization occurred in initially interrogated vessel.
b
Patient‐oriented composite outcomes include all‐cause mortality, any myocardial infarction, and any revascularization.