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. 2020 Apr 4;9(7):e015154. doi: 10.1161/JAHA.119.015154

Figure 1. Metformin treatment reduced blood pressure and normalized in vivo glucose uptake rates in SHR hearts.

Figure 1

A, MAP in WKY rats (n=6), SHR (n=6), and SHR treated with metformin (300 mg/kg per day) for 3 months (SHR+M) (n=6). B, In vivo FDG PET images normalized to (SUV). C, Glucose uptake rates (Ki) computed from in vivo dynamic FDG PET images. All data are shown as mean±SE. FDG PET, fluorodeoxyglucose positron emission tomography; MAP, mean arterial pressure; SHR, spontaneously hypertensive rats; SUV, standardized uptake value; WKY, Wistar–Kyoto.