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. 2020 Apr 2;9(7):e014146. doi: 10.1161/JAHA.119.014146

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© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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TMEM106B, but not TMEM100, is significantly upregulated in coronary arteries from coronary artery disease (CAD) patients and correlated with downregulation of ANRIL.

A, Relative expression levels of ANRIL as determined by quantitative reverse transcription‐polymerase chain reaction from coronary artery tissues from CAD patients and the age‐matched non‐CAD individuals (n=6 tissues or study subjects/group). B, Relative expression levels of TMEM106B as determined by quantitative reverse transcription‐polymerase chain reaction from coronary artery tissues from CAD patients and the age‐matched non‐CAD individuals (n=6 tissues or study subjects/group). C, Relative expression levels of TMEM100 as determined by qRT‐PCR from coronary artery tissues from CAD patients and the age‐matched non‐CAD individuals (n=6 tissues or study subjects/group). Statistical analysis was performed using unpaired, 2‐tailed Student t tests.