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. 2020 Mar 23;9(7):e014501. doi: 10.1161/JAHA.119.014501

Figure 1.

Figure 1

Mitochondrial transplantation studies in a glance. Feasibility of mitochondrial transplantation (autologous, non‐autologous, and interspecies) was demonstrated using (A) wide‐field time‐lapse (Olympus, Tokyo, Japan) and (B) confocal (Zeiss Microscopy, Jena, Germany) and (C) holotomography microscopy (Nanolive SA, Tolochenaz, Switzerland). Bioenergetics consequences of non‐autologous mitochondrial transplantation were studied using a Seahorse Extracellular Flux Analyzer (Agilent Technologies, Santa Clara, CA) (A) at 2, (B) 7, (C) 14, and (D) 28 days post‐transplantation. Mitochondrial superoxide was measured using MitoSOX Red Mitochondrial Superoxide Indicator (Thermo Fisher Scientific, Waltham, MA).