Table 2.

Comparison of Indexed Volume for Coronary Plaque Subtypes and CAC Score Stratified by the Exercise MET Groups in Uni‐ and Multivariate Analyses

	MET Groups			Univariate		Adjusted
	Group 1 n=77 4.0 to 8.1 METs	Group 2 n=98 8.2 to 10.5 METs	Group 3 n=95 ≥10.6 METs	ANOVA P Value	P Value Group 1 vs Group 3	β	P Valuea
Plaque subtypesb
Fatty plaque	7.6 [4.0, 12.8]	8.5 [4.1, 13.1]	9.9 [6.8, 15.3]	0.008	0.008	0.63	0.23
Fibrous plaque	12.3 [7.4, 21.5]	13.4 [7.3, 22.9]	20.6 [12.1, 27.3]	<0.001	<0.001	1.96	0.028
Noncalcified plaque	22.5 [11.6, 33.8]	21.6 [11.2, 35.6]	31.3 [18.3, 42.6]	0.001	0.002	2.60	0.064
Total plaque	23.9 [14.7, 41.0]	25.5 [15.0, 41.4]	39.5 [22.9, 47.6]	0.001	0.002	3.50	0.038
CACc	542.9 [227.4, 1327.3]	461.9 [84.0, 1216.1]	297.8 [120.4, 769.8]	0.050	0.011	−241.3	0.008

Data presented as median [interquartile range]. CAC indicates coronary artery calcium score; LDL‐C, low‐density lipoprotein cholesterol; and MET, metabolic equivalent of task.

^aAdjusted for age, sex, body mass index, diastolic blood pressure, diabetes mellitus status, level of LDL‐C and triglyceride, and medications, which include statin, angiotensin receptor blocker, thiazide diuretic, furosemide, and calcium‐channel blocker. Bonferroni adjusted P values are P=1.0 for fatty plaque; P=0.14 for fibrous plaque; P=0.32 for noncalcified plaque; P=0.19 for total plaque; and P=0.04 for CAC score.

^bPlaque volume expressed as mm³ divided by artery segment length (mm).

^cCAC score using Agatston technique and expressed in Agatston units.