Table 3.
Association of Baseline RV Strain and Strain Rate With Risk and Rate of Structural Progression by PSAX‐RVOT, PLAX‐RVOT, and RV‐FAC
| Structural Progression | Quartile of 5‐y Rate of Change (1=Best, 4=Worst) | |||||||
|---|---|---|---|---|---|---|---|---|
| Yes | No | P Value* | 1 | 2 | 3 | 4 | P Value† | |
| PSAX RVOT | ||||||||
| RV strain, %, mean±SD | −15.4±4.5 | −22.7±3.9 | 0.007 | −22.7±3.6 | −20.4±5.4 | −15.5±4.5 | −14.5±4.8 | 0.001 |
| RV strain rate, 1/s, mean±SD | −0.64±0.21 | −0.97±0.23 | 0.003 | −0.91±0.18 | −0.90±0.31 | −0.68±0.28 | −0.59±0.17 | 0.011 |
| PLAX RVOT | ||||||||
| RV strain, %, mean±SD | −17.3±4.9 | −20.6±6.6 | 0.160 | −20.9±7.0 | −19.5±4.3 | −18.3±3.7 | −14.6±5.5 | 0.011 |
| RV strain rate, 1/s, mean±SD | −0.71±0.25 | −0.91±0.27 | 0.043 | −0.87±0.16 | −0.90±0.34 | −0.76±0.26 | −0.57±0.22 | 0.008 |
| RV‐FAC | ||||||||
| RV strain, %, mean±SD | −18.6±5.7 | −16.8±6.4 | 0.505 | −15.9±7.0 | −17.0±6.1 | −18.9±6.7 | −19.2±4.2 | 0.219 |
| RV strain rate, 1/s, mean±SD | −0.79±0.32 | −0.71±0.24 | 0.497 | −0.63±0.28 | −0.74±0.22 | −0.84±0.40 | −0.78±0.20 | 0.254 |
RV strain and strain rate are compared between progressors and nonprogressors and across quartiles of 5‐y rate of change. PLAX indicates parasternal long axis; PSAX, parasternal short axis; RV, right ventricular; RV‐FAC, right ventricular fractional area change; and RVOT, right ventricular outflow tract.
*
P values from multivariable logistic regression (adjusting for age and sex).
†
P values from ordinal logistic regression (adjusting for age and sex).