Table 2.
Patients with SARS-CoV-2 infection (n=50) | Historical Controls (n=50) | P value | |
---|---|---|---|
Placental weight | |||
<10th percentile | 7 (14) | 10 (20) | .87 |
10th–90th percentile | 40 (80) | 37 (74) | |
>90th percentile | 3 (6) | 3 (6) | |
Maternal vascular malperfusion | |||
Accelerated villous maturation | 0 | 1 (2) | 1 |
Decidual vasculopathy | 0 | 1 (2) | 1 |
Distal villous hypoplasia | 2 (4) | 1 (2) | 1 |
Excessive infarction | 4 (8) | 4 (8) | 1 |
Old hemorrhage in membranes | 1 (2) | 2 (4) | 1 |
Fetal vascular malperfusion | 4 (8) | 6 (12) | .74 |
Increased perivillous fibrin | 6 (12) | 7 (14) | 1 |
Intervillous thrombus | 13 (26) | 8 (16) | .33 |
Delayed villous maturation | 10 (20) | 13 (26) | .64 |
Villitis | 2 (4) | 1 (2) | 1 |
Chorionitis | 11 (22) | 8 (16) | .61 |
Amnionitis | 9 (18) | 4 (8) | .23 |
Umbilical vasculitis | 7 (14) | 8 (16) | 1 |
Retroplacental thrombus | 2 (4) | 0 | .5 |
Chorangiosis | 3 (6) | 1 (2) | .62 |
Chorangioma | 0 | 1 (2) | 1 |
Meconium staining | 9 (18) | 5 (10) | .39 |
Data are presented as number (percentage).
SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
Gulersen et al. Placental histopathologic changes after maternal SARS-CoV-2 infection. AJOG MFM 2020.